“If you throw a rock into water it sinks; if you throw a stick into water it floats; if you throw a man into water he must decide whether to sink or swim.”
– Ludwig von Mises
Among other things, that’s as pithy a summary as you’re gonna get of the difference between the natural sciences and the social sciences.

Indeed, however, those people who try to “prove” economic theories by using e.g. statistics, as the mathematical (not in the eyes of pure mathematicians, though) school tries time and again, are similar to who would try and prove Pythagoras wrong by measuring millions of flat triangles only to come up with the news that not all of them are 180 degrees (and that, with regulation, that value could be better adhered to, if you listen to them long enough).